Opioid overdoses and deaths have hit Kentucky’s three northernmost counties, which represent the second largest metropolitan area in the state. As the crisis unfolded, the community rallied to respond. The goal was to tear down silos and rethink how existing services might be repurposed. A leading player in the realignment is the Kenton County Detention Center, where a 125-bed unit was redesigned as a treatment center for inmates addicted to heroin and other drugs. Early findings show impressive results, as highlighted in a New York Times op-ed column in June 2017, “Addicts Need Help. Jails Could Have the Answer.” The criminal justice, medical and social work professionals who collaborated on the inmate treatment unit are now designing a Quick Response Team to keep people who overdose out of jail and get them into treatment. It’s an evidence-based approach that will be monitored and evaluated in real time, with support from Northern Kentucky University. It’s also an approach that can be replicated elsewhere in America. Our panelists will offer guidance on how to adopt the approach.